For the prevention of anaphylactoid reactions during glazmafereza receiving inhibitor is temporarily stopped prior to the procedure.
Angioneurotic edema of the face, extremities, lips, mucous membranes, tongue, vocal cords, and / or larynx may develop during treatment with preventivo kondome mix testosterone inhibitors, particularly during the first few weeks of treatment. In rare cases, severe angioedema may occur against the background of a prolonged use of the drug. In such cases, fosinopril should be lifted immediately and apply anti-hypertensive drug other pharmacological class.
In patients with hypertension, symptomatic hypotension with the use inhibitors most often develops after intensive treatment with diuretics, diet, limiting sodium chloride, against diarrhea, vomiting, or in patients on hemodialysis.
in patients with heart failure with concomitant renal failure or without increasing the risk of a sharp decline in blood pressure in the background of hyponatremia after previously conducted intensive diuretic therapy, as well as in elderly patients.
Temporary hypotension is not a contraindication for the use of the drug after of measures aimed at increasing the bCC. To reduce the risk of symptomatic hypotension in patients who take diuretics, it is recommended to stop taking them 2-3 days prior to treatment , If unable to cancel diuretics, treatment should start with the lowest dose of 10 mg. Further dose escalation is under the control of blood pressure.
In some patients with heart failure, who initially had normal or low blood pressure, with the start of drug administration further moderate reduction in systemic blood pressure, which is a common effect at the beginning of the drug.
During the application may cause a dry cough, which disappears after discontinuation of the drug. If necessary, treatment can be continued.
In the case of jaundice or a significant increase in activity of “liver” enzymes, inhibitors should be stopped and to provide the patient a thorough medical examination.
While receiving inhibitors rarely observed intestinal mucosa swelling, often in the absence of nausea and vomiting, which disappeared after discontinuation inhibitors. Swelling of the intestinal mucosa should be considered in the differential diagnosis in patients complaining of abdominal pain that has developed during treatment with preventivo kondome mix testosteroneinhibitors.
When surgery (general anesthesia), thus enabling the development of arterial hypotension.
It should inform the anesthetist about the use if patient planned for anesthesia or surgery. Treatment inhibitor should be discontinued one day prior to surgery.
Patients receiving , caution should be exercised during exercise or in hot weather because of the risk of development of dehydration and hypotension due to a decrease.
It is not recommended to use the together with lithium therapy. If necessary, the use of such a combination is necessary to monitor the concentration of lithium in blood plasma.
In children and adolescents under the age of 18 years (safety and efficacy not established).
Effects on ability to drive vehicles and working with machinery
Use caution while using the preventivo kondome mix testosteronedue to the potential for adverse reactions that may adversely affect the ability to road management and the performance of potentially hazardous activities that require high concentration and speed of psychomotor reactions .